Product Name :
TIMP-4 (S206) Peptide Applications :
Blocking Background :
TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metallopro teinases-1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 was found to be identical to EPA (erythroidpotentiation activity). Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart and low levels of TIMP-4 are expressed in liver, brain, lung, thymus and spleen. Alternative Name :
TIMP4; Tissue inhibitor of metalloproteinases 4; TIMP-4; TIMP4; 7079; TIMP4; 601915; Q99727; Swiss-Prot :
Q99727 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TIMP-4 (S206). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1477 TIMP-4 (S206) pAb.
TIMP-4 (S206) Peptide Applications :
Blocking Background :
TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metallopro teinases-1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 was found to be identical to EPA (erythroidpotentiation activity). Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart and low levels of TIMP-4 are expressed in liver, brain, lung, thymus and spleen. Alternative Name :
TIMP4; Tissue inhibitor of metalloproteinases 4; TIMP-4; TIMP4; 7079; TIMP4; 601915; Q99727; Swiss-Prot :
Q99727 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TIMP-4 (S206). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1477 TIMP-4 (S206) pAb.
Blocking peptide available as BS1477PP