Product Name :
SAE2 (S621) Peptide Applications :
Blocking Background :
The human UBiquitin Activating domain 2 (UBA2) gene is located on chromosome 19q12. Human UBA2 could form a beta mercaptoethanol-sensitive conjugate with members of the sentrin family, but not with ubiquitin of NEDD8 in the presence of AOS1. The recombinant proteins, Sua1p and hUba2, form a complex. In this complex, hUba2 binds SUMO-1, which gives the complex the activity of the SUMO-1 activating enzyme. Therefore, UBA2 has been found to be a component of the sentrin-activating enzyme complex. Alternative Name :
Ubiquitin-like 2 activating enzyme E1B; SUMO-1 activating enzyme subunit 2; Anthracycline-associated resistance ARX; HRIHFB2115 Swiss-Prot :
Q9UBT2 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide SAE2 (S621). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1485 SAE2 (S621) pAb.
SAE2 (S621) Peptide Applications :
Blocking Background :
The human UBiquitin Activating domain 2 (UBA2) gene is located on chromosome 19q12. Human UBA2 could form a beta mercaptoethanol-sensitive conjugate with members of the sentrin family, but not with ubiquitin of NEDD8 in the presence of AOS1. The recombinant proteins, Sua1p and hUba2, form a complex. In this complex, hUba2 binds SUMO-1, which gives the complex the activity of the SUMO-1 activating enzyme. Therefore, UBA2 has been found to be a component of the sentrin-activating enzyme complex. Alternative Name :
Ubiquitin-like 2 activating enzyme E1B; SUMO-1 activating enzyme subunit 2; Anthracycline-associated resistance ARX; HRIHFB2115 Swiss-Prot :
Q9UBT2 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide SAE2 (S621). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1485 SAE2 (S621) pAb.
Blocking peptide available as BS1485PP