Ku-70 (R586) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Ku-70 (R586) Peptide Applications :
Blocking Background :
The Ku protein is localized in the nucleus and is composed of subunits referred to as Ku-70 (or p70) and Ku-86 (or p86), which is also known by the synonym Ku-80 (or p80). Ku was first described as an autoantigen to which antibodies were produced in a patient with scleroderma-polymyositis overlap syndrome, and was later found in the sera of patients with other rheumatic diseases. Both subunits of the Ku protein have been cloned, and a number of functions have been proposed for Ku, including cell signaling, DNA replication and transcriptional activation. Alternative Name :
XRCC6; CTC75; CTCBF; D22S671; D22S731; EC 3.6.1.-; G22P1; KU70; ML8; TLAA Swiss-Prot :
P12956 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Ku-70 (R586). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1498 Ku-70 (R586) pAb.
Ku-70 (R586) Peptide Applications :
Blocking Background :
The Ku protein is localized in the nucleus and is composed of subunits referred to as Ku-70 (or p70) and Ku-86 (or p86), which is also known by the synonym Ku-80 (or p80). Ku was first described as an autoantigen to which antibodies were produced in a patient with scleroderma-polymyositis overlap syndrome, and was later found in the sera of patients with other rheumatic diseases. Both subunits of the Ku protein have been cloned, and a number of functions have been proposed for Ku, including cell signaling, DNA replication and transcriptional activation. Alternative Name :
XRCC6; CTC75; CTCBF; D22S671; D22S731; EC 3.6.1.-; G22P1; KU70; ML8; TLAA Swiss-Prot :
P12956 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Ku-70 (R586). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1498 Ku-70 (R586) pAb.
Blocking peptide available as BS1498PP