ALOX5 (E267) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
ALOX5 (E267) Peptide Applications :
Blocking Background :
5-lipoxygenase (5-LO) is expressed primarily in polymorphonuclear leukocytes, macrophages, and mast cells. 5-LO performs the first two catalytic reactions in the biosynthesis of leukotrienes, lipid metabolites that induce contractions of airway smooth muscle and increase vascular permeability during anaphylaxis. The cellular localization of 5-LO varies between cell types. In activated blood polymorphonuclear leukocytes 5-LO undergoes calcium dependent translocation from the cytosol to the nuclear envelope. In alveolar macrophages, the majority of 5-LO is localized in the nucleus and, upon activation of these cells, intranuclear 5-LO binds to the nuclear membrane. Alternative Name :
Arachidonate 5-lipoxygenase; 5-LO; 5-lipoxygenase; ALOX5; LOG5 Swiss-Prot :
P09917 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ALOX5 (E267). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1506 ALOX5 (E267) pAb.
ALOX5 (E267) Peptide Applications :
Blocking Background :
5-lipoxygenase (5-LO) is expressed primarily in polymorphonuclear leukocytes, macrophages, and mast cells. 5-LO performs the first two catalytic reactions in the biosynthesis of leukotrienes, lipid metabolites that induce contractions of airway smooth muscle and increase vascular permeability during anaphylaxis. The cellular localization of 5-LO varies between cell types. In activated blood polymorphonuclear leukocytes 5-LO undergoes calcium dependent translocation from the cytosol to the nuclear envelope. In alveolar macrophages, the majority of 5-LO is localized in the nucleus and, upon activation of these cells, intranuclear 5-LO binds to the nuclear membrane. Alternative Name :
Arachidonate 5-lipoxygenase; 5-LO; 5-lipoxygenase; ALOX5; LOG5 Swiss-Prot :
P09917 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ALOX5 (E267). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1506 ALOX5 (E267) pAb.
Blocking peptide available as BS1506PP