Bcl-2 (P65) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Bcl-2 (P65) Peptide Applications :
Blocking Background :
Bcl-2 is one among many key regulators of apoptosis which are essential for proper development, tissue homeostasis and protection against foreign pathogens. Human Bcl-2 is a 26 kDa, membraneassociated, anti-apoptotic oncoprotein that can promote cell survival through protein-protein interactions with other Bcl-2 related family members, such as the death suppressors Bcl-xL, Mcl-1, Bcl-w and A1, or the death agonists Bax, Bak, Bik, Bad and BID. The anti-apoptotic function of Bcl-2 can also be regulated through proteolytic processing and phosphorylation. Bcl-2 may promote cell survival by interfering with the activation of the cytochrome c/Apaf-1 pathway through stabilization of the mitochondrial membrane. Alternative Name :
Apoptosis regulator Bcl-2; Bcl 2; BCL2 Swiss-Prot :
P10415 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Bcl-2 (P65). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1511 Bcl-2 (P65) pAb.
Bcl-2 (P65) Peptide Applications :
Blocking Background :
Bcl-2 is one among many key regulators of apoptosis which are essential for proper development, tissue homeostasis and protection against foreign pathogens. Human Bcl-2 is a 26 kDa, membraneassociated, anti-apoptotic oncoprotein that can promote cell survival through protein-protein interactions with other Bcl-2 related family members, such as the death suppressors Bcl-xL, Mcl-1, Bcl-w and A1, or the death agonists Bax, Bak, Bik, Bad and BID. The anti-apoptotic function of Bcl-2 can also be regulated through proteolytic processing and phosphorylation. Bcl-2 may promote cell survival by interfering with the activation of the cytochrome c/Apaf-1 pathway through stabilization of the mitochondrial membrane. Alternative Name :
Apoptosis regulator Bcl-2; Bcl 2; BCL2 Swiss-Prot :
P10415 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Bcl-2 (P65). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1511 Bcl-2 (P65) pAb.
Blocking peptide available as BS1511PP