Raf-B (A597) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Raf-B (A597) Peptide Applications :
Blocking Background :
Raf-1 is a cytoplasmic protein with intrinsic serine/threonine activity. It is broadly expressed in nearly all cell lines tested to date and is the cellular homolog of v-Raf, the product of the transforming gene of the 3611 strain of murine sarcoma virus. The unregulated kinase activity of the v-Raf protein has been associated with transformation and mitogenesis while the activity of Raf-1 is normally suppressed by a regulatory N-terminal domain. Raf-A, a second member of the Raf gene family of serine/threonine protein kinases, exhibits substantial homology to Raf-1 within the kinase domain of the two molecules, but less homology elsewhere. Expression of Raf-B is highly restricted with highest levels in the cerebrum and testis. Alternative Name :
BRAF; B-RAF; B-RAF-1; BRAF1; EC 2.7.11.1; MGC126806; MGC138284; P94; RAFB1 Swiss-Prot :
P15056 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Raf-B (A597). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1514 Raf-B (A597) pAb.
Raf-B (A597) Peptide Applications :
Blocking Background :
Raf-1 is a cytoplasmic protein with intrinsic serine/threonine activity. It is broadly expressed in nearly all cell lines tested to date and is the cellular homolog of v-Raf, the product of the transforming gene of the 3611 strain of murine sarcoma virus. The unregulated kinase activity of the v-Raf protein has been associated with transformation and mitogenesis while the activity of Raf-1 is normally suppressed by a regulatory N-terminal domain. Raf-A, a second member of the Raf gene family of serine/threonine protein kinases, exhibits substantial homology to Raf-1 within the kinase domain of the two molecules, but less homology elsewhere. Expression of Raf-B is highly restricted with highest levels in the cerebrum and testis. Alternative Name :
BRAF; B-RAF; B-RAF-1; BRAF1; EC 2.7.11.1; MGC126806; MGC138284; P94; RAFB1 Swiss-Prot :
P15056 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Raf-B (A597). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1514 Raf-B (A597) pAb.
Blocking peptide available as BS1514PP