CD3 ζ (K36) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
CD3 ζ (K36) Peptide Applications :
Blocking Background :
Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering. The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. CD3-zeta forms either homodimers or heterodimers with CD3-eta. Interacts with SLA and SLA2. Interacts with DOCK2 and TRAT1. Interacts with HIV-1; this interaction up-regulates the expression of the Fas ligand (FASLG) at the cell surface. Interacts with HIV-2 Nef protein; this interaction induces down-regulation of cell surface TCR/CD3 complexes. Alternative Name :
T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain; CD247; CD247; CD3Z; T3Z; TCRZ; CD3ζ; CD3-ζ Swiss-Prot :
P20963 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CD3 ζ (K36). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1521 CD3 ζ (K36) pAb.
CD3 ζ (K36) Peptide Applications :
Blocking Background :
Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering. The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. CD3-zeta forms either homodimers or heterodimers with CD3-eta. Interacts with SLA and SLA2. Interacts with DOCK2 and TRAT1. Interacts with HIV-1; this interaction up-regulates the expression of the Fas ligand (FASLG) at the cell surface. Interacts with HIV-2 Nef protein; this interaction induces down-regulation of cell surface TCR/CD3 complexes. Alternative Name :
T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain; CD247; CD247; CD3Z; T3Z; TCRZ; CD3ζ; CD3-ζ Swiss-Prot :
P20963 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CD3 ζ (K36). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1521 CD3 ζ (K36) pAb.
Blocking peptide available as BS1521PP