ERα (K531) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
ERα (K531) Peptide Applications :
Blocking Background :
Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor uperfamily of ligand-activated transcription factors. Estrogen receptors, ncluding ERα and ERβ, contain DNA binding and ligand binding domains nd are critically involved in regulating the normal function of reproductive issues. ERα and ERβ have been shown to be differentially activated by various igands. Receptor-ligand interactions trigger a cascade of events, including issociation from heat shock proteins, receptor dimerization, phosphorylation nd the association of the hormone activated receptor with specific regulatory lements in target genes. Evidence suggests that ERα and ERβ may be egulated by distinct mechanisms even though they share many functional characteristics. Alternative Name :
Estrogen receptor; ER-alpha; ER; ESR1; ESR; NR3A1 Swiss-Prot :
P03372 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ERα (K531). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1535 ERα (K531) pAb.
ERα (K531) Peptide Applications :
Blocking Background :
Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor uperfamily of ligand-activated transcription factors. Estrogen receptors, ncluding ERα and ERβ, contain DNA binding and ligand binding domains nd are critically involved in regulating the normal function of reproductive issues. ERα and ERβ have been shown to be differentially activated by various igands. Receptor-ligand interactions trigger a cascade of events, including issociation from heat shock proteins, receptor dimerization, phosphorylation nd the association of the hormone activated receptor with specific regulatory lements in target genes. Evidence suggests that ERα and ERβ may be egulated by distinct mechanisms even though they share many functional characteristics. Alternative Name :
Estrogen receptor; ER-alpha; ER; ESR1; ESR; NR3A1 Swiss-Prot :
P03372 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ERα (K531). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1535 ERα (K531) pAb.
Blocking peptide available as BS1535PP