Product Name :
MITF (G174) Peptide Applications :
Blocking Background :
MITF is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. Plays a critical role in the differentiation of various cell types including neural crest- derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium. Two isoforms are known: the M-isoform is expressed exclusively in melanocytes, while the A-isoform has a much broader range of expression. Mutations in MITF can lead to Waardenburg syndrome. Ten alternatively spliced isoforms have been described. Alternative Name :
MITF; WS2A; bHLHe32; BHLHE32; Microphthalmia-associated transcription factor Swiss-Prot :
O75030 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide MITF (G174). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1550 MITF (G174) pAb.
MITF (G174) Peptide Applications :
Blocking Background :
MITF is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. Plays a critical role in the differentiation of various cell types including neural crest- derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium. Two isoforms are known: the M-isoform is expressed exclusively in melanocytes, while the A-isoform has a much broader range of expression. Mutations in MITF can lead to Waardenburg syndrome. Ten alternatively spliced isoforms have been described. Alternative Name :
MITF; WS2A; bHLHe32; BHLHE32; Microphthalmia-associated transcription factor Swiss-Prot :
O75030 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide MITF (G174). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1550 MITF (G174) pAb.
Blocking peptide available as BS1550PP