mTOR (P2476) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
mTOR (P2476) Peptide Applications :
Blocking Background :
mTOR, or FKBP12-rapamycin associated protein (FRAP), is one of a family of proteins involved in cell cycle progression, DNA recombination, and DNA damage detection. In rat, it is a 245-kDa protein (symbolized RAFT1) with significant homology to the Saccharomyces cerevisiae protein TOR1 and has been shown to associate with the immunophilin FKBP12 in a rapamycin-dependent fashion. The FKBP12-rapamycin complex is known to inhibit progression through the G1 cell cycle stage by interfering with mitogenic signaling pathways involved in G1 progression in several cell types, as well as in yeast. The binding of FRAP to FKBP12-rapamycin correlated with the ability of these ligands to inhibit cell cycle progression. Alternative Name :
mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; Rapamycin target protein; RAPT1; Mammalian target of rapamycin; mTOR; mTOR; FK506 binding protein12-rapamycin associated protein 1. FK506 binding protein12-ra Swiss-Prot :
P42345 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide mTOR (P2476). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1555 mTOR (P2476) pAb.
mTOR (P2476) Peptide Applications :
Blocking Background :
mTOR, or FKBP12-rapamycin associated protein (FRAP), is one of a family of proteins involved in cell cycle progression, DNA recombination, and DNA damage detection. In rat, it is a 245-kDa protein (symbolized RAFT1) with significant homology to the Saccharomyces cerevisiae protein TOR1 and has been shown to associate with the immunophilin FKBP12 in a rapamycin-dependent fashion. The FKBP12-rapamycin complex is known to inhibit progression through the G1 cell cycle stage by interfering with mitogenic signaling pathways involved in G1 progression in several cell types, as well as in yeast. The binding of FRAP to FKBP12-rapamycin correlated with the ability of these ligands to inhibit cell cycle progression. Alternative Name :
mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; Rapamycin target protein; RAPT1; Mammalian target of rapamycin; mTOR; mTOR; FK506 binding protein12-rapamycin associated protein 1. FK506 binding protein12-ra Swiss-Prot :
P42345 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide mTOR (P2476). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1555 mTOR (P2476) pAb.
Blocking peptide available as BS1555PP