Product Name :
Sp1 (G447) Peptide Applications :
Blocking Background :
Sp1 is a sequence-specific transcription factor that recognizes GGGGCGGGGC and closely related sequences, which are often referred to as GC boxes. Sp1 was initially identified as a HeLa cell-derived factor that selectively activates in vitro transcription from the SV40 promoter and binds to the multiple GC boxes in the 21 bp repeated elements in SV40. The sequence specificity of DNA binding is conferred by Zn (II) fingers, whereas a different region of Sp1 appears to regulate the affinity of DNA binding. Sp1 belongs to a subgroup of transcription factors that are phosphorylated upon binding to promoter sequences. Alternative Name :
Transcription factor Sp1; SP1; TSFP1 Swiss-Prot :
P08047 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Sp1 (G447). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1598 Sp1 (G447) pAb.

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Blocking peptide available as BS1598PP