WASP (E284) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
WASP (E284) Peptide Applications :
Blocking Background :
The Wiskott-Aldrich syndrome (WAS) is a disorder that results from a monogenic defect that has been mapped to the short arm of the X chromosome at Xp11.23. WAS is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative disease. The gene that is mutated in the syndrome encodes a 53 kDa proline-rich protein of unknown function designated WAS protein (WASP). A clue to WASP function came from the observation that T cells from affected males had an irregular cellular morphology and a disarrayed cytoskeleton suggesting the involvement of WASP in cytoskeletal organization. Close examination of the WASP sequence revealed a putative Cdc42/Rac interacting domain, homologous with those found in PAK65 and ACK. Subsequent investigation has shown WASP to be a true downstream effector of Cdc42. Alternative Name :
IMD2; SCNX; THC; THC1; Thrombocytopenia 1 (X linked); U42471; Was; WASp; WASP; Wiskott Aldrich syndrome (eczema thrombocytopenia); Wiskott Aldrich syndrome protein; Wiskott-Aldrich syndrome protein; Swiss-Prot :
P42768 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide WASP (E284). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1607 WASP (E284) pAb.
WASP (E284) Peptide Applications :
Blocking Background :
The Wiskott-Aldrich syndrome (WAS) is a disorder that results from a monogenic defect that has been mapped to the short arm of the X chromosome at Xp11.23. WAS is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative disease. The gene that is mutated in the syndrome encodes a 53 kDa proline-rich protein of unknown function designated WAS protein (WASP). A clue to WASP function came from the observation that T cells from affected males had an irregular cellular morphology and a disarrayed cytoskeleton suggesting the involvement of WASP in cytoskeletal organization. Close examination of the WASP sequence revealed a putative Cdc42/Rac interacting domain, homologous with those found in PAK65 and ACK. Subsequent investigation has shown WASP to be a true downstream effector of Cdc42. Alternative Name :
IMD2; SCNX; THC; THC1; Thrombocytopenia 1 (X linked); U42471; Was; WASp; WASP; Wiskott Aldrich syndrome (eczema thrombocytopenia); Wiskott Aldrich syndrome protein; Wiskott-Aldrich syndrome protein; Swiss-Prot :
P42768 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide WASP (E284). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1607 WASP (E284) pAb.
Blocking peptide available as BS1607PP