HDAC6 (Q18) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
HDAC6 (Q18) Peptide Applications :
Blocking Background :
HDAC6 is a member of the class II mammalian histone deacetylases. Human HDAC6 is composed of 1215 amino acid residues. It possesses two separate putative catalytic domains. Both catalytic domains are fully functional HDACs and contribute independently to the overall activity of HDAC6 protein. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. The expression of HDAC6 is tightly linked to the state of cell differentiation. HDAC6 may participate in coordinating expression of a group of genes involved in the remodelling of chromatin during cell differentiation. Alternative Name :
Histone deacetylase 6; HD6; HDAC 6; KIAA0901; JM21 Swiss-Prot :
Q9UBN7 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide HDAC6 (Q18). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1652 HDAC6 (Q18) pAb.
HDAC6 (Q18) Peptide Applications :
Blocking Background :
HDAC6 is a member of the class II mammalian histone deacetylases. Human HDAC6 is composed of 1215 amino acid residues. It possesses two separate putative catalytic domains. Both catalytic domains are fully functional HDACs and contribute independently to the overall activity of HDAC6 protein. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. The expression of HDAC6 is tightly linked to the state of cell differentiation. HDAC6 may participate in coordinating expression of a group of genes involved in the remodelling of chromatin during cell differentiation. Alternative Name :
Histone deacetylase 6; HD6; HDAC 6; KIAA0901; JM21 Swiss-Prot :
Q9UBN7 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide HDAC6 (Q18). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1652 HDAC6 (Q18) pAb.
Blocking peptide available as BS1652PP