Product Name :
JAK3 (I781) Peptide Applications :
Blocking Background :
Jak3 (Janus Kinase 3) belongs to the family of non-receptor Janus tyrosine kinases, which regulate a spectrum of cellular functions downstream of activated cytokine receptors in the lympho-hematopoietic system. Immunological stimuli, such as interferons and cytokines, induce recruitment of Stat transcription factors to cytokine receptor-associated JAK3. JAK3 then phosphorylates proximal Stat factors, which subsequently dimerize, translocate to the nucleus and bind to cis elements upstream of target gene promoters to regulate transcription. Alternative Name :
JAK3; EC 2.7.10.2; JAK-3; JAK3; JAKL; L-JAK; LJAK Swiss-Prot :
P52333 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide JAK3 (I781). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1671 JAK3 (I781) pAb.

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Blocking peptide available as BS1671PP