PDGFR-α (S1057) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
PDGFR-α (S1057) Peptide Applications :
Blocking Background :
Platelet-derived growth factor receptors exhibit tyrosine-protein kinase activity and have been implicated in the control of cell proliferation, survival and migration. PDGF receptors, PDGFR-alpha and PDGFR-beta, have 5 extracellular immunoglobulin-like domains and an intracellular tyrosine kinase domain. Upon binding a PDGF, the receptors form homo-and heterodimers. Dimerization of the receptors results in phosphorylation in the complex. More than 10 different SH2-domain-containing molecules have been shown to bind to different autophosphorylation sites in the PDGF-alpha and beta receptors. PDGF alpha receptors are expressed in oligodendrocyte progenitor cells and PDGF beta receptors are expressed on neurons. Alternative Name :
PDGF Receptor alpha ( phospho Y742 ); EC 2.7.10.1; PDGF-R-alpha; CD140 antigen-like family member A; CD140a antigen; CD140a antigen; PDGFR alpha Swiss-Prot :
P16234 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PDGFR-α (S1057). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1684 PDGFR-α (S1057) pAb.
PDGFR-α (S1057) Peptide Applications :
Blocking Background :
Platelet-derived growth factor receptors exhibit tyrosine-protein kinase activity and have been implicated in the control of cell proliferation, survival and migration. PDGF receptors, PDGFR-alpha and PDGFR-beta, have 5 extracellular immunoglobulin-like domains and an intracellular tyrosine kinase domain. Upon binding a PDGF, the receptors form homo-and heterodimers. Dimerization of the receptors results in phosphorylation in the complex. More than 10 different SH2-domain-containing molecules have been shown to bind to different autophosphorylation sites in the PDGF-alpha and beta receptors. PDGF alpha receptors are expressed in oligodendrocyte progenitor cells and PDGF beta receptors are expressed on neurons. Alternative Name :
PDGF Receptor alpha ( phospho Y742 ); EC 2.7.10.1; PDGF-R-alpha; CD140 antigen-like family member A; CD140a antigen; CD140a antigen; PDGFR alpha Swiss-Prot :
P16234 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PDGFR-α (S1057). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1684 PDGFR-α (S1057) pAb.
Blocking peptide available as BS1684PP