Product Name :
RPA2 (A17) Peptide Applications :
Blocking Background :
RPA is a major damage-recognition protein involved in the early stages of nucleotide excision repair. It can also play a role in telomere maintenance. The C-terminus of RPA 32 can specfically intereact with the DNA repair enzyme UNG2 and repair factors XPA and Rad52, each of which functions in a different repair pathway. In addition, RPA 32 binds specifically to the SH2 domain of Stat3 in vivo, and overexpression of RPA 32 corresponds to the augmented growth factor-stimulated tyrosine phosphorylation and transcription activities of Stat3. Alternative Name :
Replication protein A 32 kDa subunit; RP-A p32; RF-A protein 2; RPA2; REPA2; RPA32; RPA34 Swiss-Prot :
P15927 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide RPA2 (A17). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1692 RPA2 (A17) pAb.
RPA2 (A17) Peptide Applications :
Blocking Background :
RPA is a major damage-recognition protein involved in the early stages of nucleotide excision repair. It can also play a role in telomere maintenance. The C-terminus of RPA 32 can specfically intereact with the DNA repair enzyme UNG2 and repair factors XPA and Rad52, each of which functions in a different repair pathway. In addition, RPA 32 binds specifically to the SH2 domain of Stat3 in vivo, and overexpression of RPA 32 corresponds to the augmented growth factor-stimulated tyrosine phosphorylation and transcription activities of Stat3. Alternative Name :
Replication protein A 32 kDa subunit; RP-A p32; RF-A protein 2; RPA2; REPA2; RPA32; RPA34 Swiss-Prot :
P15927 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide RPA2 (A17). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1692 RPA2 (A17) pAb.
Blocking peptide available as BS1692PP