Skp1 p19 (P72) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Skp1 p19 (P72) Peptide Applications :
Blocking Background :
Cyclin A accumulates prior to cyclin B in the cell cycle, appears to be involved in control of S phase and has been shown to associate with cyclin dependent kinase-2 (Cdk2). In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcription factors DP-1 and E2F and retinoblastoma protein p110. Two cyclin A-Cdk2 complex binding proteins, Skp1 p19 and Skp2 p45, have been described. Although the Skps (S phase kinase-associated proteins) associate with the active cyclin A-Cdk2 complex, they do not exhibit any regulatory effects on the complex. Abolition of Skp2 p45 function by either microinjection of anti-p45 antibodies or addition of antisense oligonucleotides prevents entry into S phase of both normal and transformed cells. Alternative Name :
p19A; RNA polymerase II elongation factor-like protein; Organ of Corti protein 2; OCP-2; OCP-II; Transcription elongation factor B; SIII; SKP1; EMC19; OCP2; SKP1A; TCEB1L Swiss-Prot :
P63208 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Skp1 p19 (P72). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1694 Skp1 p19 (P72) pAb.
Skp1 p19 (P72) Peptide Applications :
Blocking Background :
Cyclin A accumulates prior to cyclin B in the cell cycle, appears to be involved in control of S phase and has been shown to associate with cyclin dependent kinase-2 (Cdk2). In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcription factors DP-1 and E2F and retinoblastoma protein p110. Two cyclin A-Cdk2 complex binding proteins, Skp1 p19 and Skp2 p45, have been described. Although the Skps (S phase kinase-associated proteins) associate with the active cyclin A-Cdk2 complex, they do not exhibit any regulatory effects on the complex. Abolition of Skp2 p45 function by either microinjection of anti-p45 antibodies or addition of antisense oligonucleotides prevents entry into S phase of both normal and transformed cells. Alternative Name :
p19A; RNA polymerase II elongation factor-like protein; Organ of Corti protein 2; OCP-2; OCP-II; Transcription elongation factor B; SIII; SKP1; EMC19; OCP2; SKP1A; TCEB1L Swiss-Prot :
P63208 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Skp1 p19 (P72). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1694 Skp1 p19 (P72) pAb.
Blocking peptide available as BS1694PP