PLC β3 (D1099) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
PLC β3 (D1099) Peptide Applications :
Blocking Background :
A total of eight mammalian PLC isozymes have been described (PLC β1, PLC β2, PLC β3, PLC β4, PLC γ1, PLC γ2, PLC δ1 and PLC δ2) with molecular weights ranging from 85 to 150 kDa. The γ-type enzymes are unique in that they contain SH2 and SH3 domains. Moreover, the two γ-type enzymes, but not the β and δ isozymes, are subject to activation by a number of protein tyrosine kinases which associate with their SH2 domains and induce their activation by phosphoryation. In contrast, activation of PLC β1, PLC β2 and PLC β3 is mediated by the α subunits of the Gq class of heterotrimeric G proteins and by certain βγ G protein subunits. The regulatory mechanisms for PLC δ1 and PLC δ2 are as yet not resolved. Alternative Name :
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase β-3; Phosphoinositide phospholipase C-β-3; Phospholipase C-β-3; PLC-β3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3; Phosphoinositide phospholipase C-beta-3; Phospholipase C-beta-3; PLC-beta-3; PLCB3; PLCβ3 Swiss-Prot :
Q01970 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PLC β3 (D1099). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1708 PLC β3 (D1099) pAb.
PLC β3 (D1099) Peptide Applications :
Blocking Background :
A total of eight mammalian PLC isozymes have been described (PLC β1, PLC β2, PLC β3, PLC β4, PLC γ1, PLC γ2, PLC δ1 and PLC δ2) with molecular weights ranging from 85 to 150 kDa. The γ-type enzymes are unique in that they contain SH2 and SH3 domains. Moreover, the two γ-type enzymes, but not the β and δ isozymes, are subject to activation by a number of protein tyrosine kinases which associate with their SH2 domains and induce their activation by phosphoryation. In contrast, activation of PLC β1, PLC β2 and PLC β3 is mediated by the α subunits of the Gq class of heterotrimeric G proteins and by certain βγ G protein subunits. The regulatory mechanisms for PLC δ1 and PLC δ2 are as yet not resolved. Alternative Name :
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase β-3; Phosphoinositide phospholipase C-β-3; Phospholipase C-β-3; PLC-β3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3; Phosphoinositide phospholipase C-beta-3; Phospholipase C-beta-3; PLC-beta-3; PLCB3; PLCβ3 Swiss-Prot :
Q01970 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PLC β3 (D1099). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1708 PLC β3 (D1099) pAb.
Blocking peptide available as BS1708PP