Product Name :
Cyclin D1 (L283) Peptide Applications :
Blocking Background :
Considerable effort directed towards the identification of G1 cyclins has led to the isolation of cyclin D, cyclin C and cyclin E. Of these, cyclin D corresponds to a putative human oncogene, designated PRAD1, which maps at the site of the Bcl1 rearrangement in certain lymphomas and leukemias. Two additional human type D cyclins, as well as their mouse homologs, have been identified. Evidence has established that members of the cyclin D family function to regulate phosphorylation of the retinoblastoma gene product, thereby activating E2F transcription factors. Alternative Name :
CCND1; BCL1; D11S287E; PRAD1; U21B31 Swiss-Prot :
P24385 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Cyclin D1 (L283). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1741 Cyclin D1 (L283) pAb.
Cyclin D1 (L283) Peptide Applications :
Blocking Background :
Considerable effort directed towards the identification of G1 cyclins has led to the isolation of cyclin D, cyclin C and cyclin E. Of these, cyclin D corresponds to a putative human oncogene, designated PRAD1, which maps at the site of the Bcl1 rearrangement in certain lymphomas and leukemias. Two additional human type D cyclins, as well as their mouse homologs, have been identified. Evidence has established that members of the cyclin D family function to regulate phosphorylation of the retinoblastoma gene product, thereby activating E2F transcription factors. Alternative Name :
CCND1; BCL1; D11S287E; PRAD1; U21B31 Swiss-Prot :
P24385 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Cyclin D1 (L283). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1741 Cyclin D1 (L283) pAb.
Blocking peptide available as BS1741PP