VDR (N204) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
VDR (N204) Peptide Applications :
Blocking Background :
The vitamin D receptor (VDR), also known as the calcitriol receptor, and also known as NR1I1 (nuclear receptor subfamily 1, group I, member 1), is a member of the nuclear receptor family of transcription factors. Upon activation by vitamin D, the VDR forms a heterodimer with the retinoid-X receptor and binds to hormone response elements on DNA resulting in expression or trans-repression of specific gene products.It is an intracellular hormone receptor that specifically binds 1,25(OH)2D3 and mediates its effects. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Alternative Name :
VDR; NR1I1; Vitamin D3 receptor; 1; 25-dihydroxyvitamin D3 receptor; Nuclear receptor subfamily 1 group I member 1; Swiss-Prot :
P11473 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide VDR (N204). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1774 VDR (N204) pAb.
VDR (N204) Peptide Applications :
Blocking Background :
The vitamin D receptor (VDR), also known as the calcitriol receptor, and also known as NR1I1 (nuclear receptor subfamily 1, group I, member 1), is a member of the nuclear receptor family of transcription factors. Upon activation by vitamin D, the VDR forms a heterodimer with the retinoid-X receptor and binds to hormone response elements on DNA resulting in expression or trans-repression of specific gene products.It is an intracellular hormone receptor that specifically binds 1,25(OH)2D3 and mediates its effects. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Alternative Name :
VDR; NR1I1; Vitamin D3 receptor; 1; 25-dihydroxyvitamin D3 receptor; Nuclear receptor subfamily 1 group I member 1; Swiss-Prot :
P11473 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide VDR (N204). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1774 VDR (N204) pAb.
Blocking peptide available as BS1774PP