Product Name :
NOS1 (Y846) Peptide Applications :
Blocking Background :
NOS activity requires homodimerization as well as three cosubstrates (L-arginine, NADPH and O2) and five cofactors or prosthetic groups (FAD, FMN, calmodulin, tetrahydrobiopterin and heme). Several distinct NOS isoforms have been described and been shown to represent the products of three distinct genes. These include two constitutive Ca2+/CaM-dependent forms of NOS, including NOS1 (also designated ncNOS) whose activity was first identified in neurons, and NOS3 (also designated ecNOS), first identified in endothelial cells. Alternative Name :
NOS1; BNOS; EC 1.14.13.39; IHPS1; N-NOS; NC-NOS; NNOS; NOS Swiss-Prot :
P29475 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide NOS1 (Y846). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1821 NOS1 (Y846) pAb.
NOS1 (Y846) Peptide Applications :
Blocking Background :
NOS activity requires homodimerization as well as three cosubstrates (L-arginine, NADPH and O2) and five cofactors or prosthetic groups (FAD, FMN, calmodulin, tetrahydrobiopterin and heme). Several distinct NOS isoforms have been described and been shown to represent the products of three distinct genes. These include two constitutive Ca2+/CaM-dependent forms of NOS, including NOS1 (also designated ncNOS) whose activity was first identified in neurons, and NOS3 (also designated ecNOS), first identified in endothelial cells. Alternative Name :
NOS1; BNOS; EC 1.14.13.39; IHPS1; N-NOS; NC-NOS; NNOS; NOS Swiss-Prot :
P29475 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide NOS1 (Y846). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1821 NOS1 (Y846) pAb.
Blocking peptide available as BS1821PP