Product Name :
PIG11 (P93) Peptide Applications :
Blocking Background :
PIG11 (p53-induced gene 11 protein), also known as TP53I11, is a 177 amino acid tumor suppressor belonging to the p53-induced protein gene (PIG) family. The PIG gene family encodes redox-controlling proteins that are involved in p53 tumor suppressor activity. It is suggested that PIG11 is involved in arsenic trioxide As(2)O(3)-induced apoptosis in certain cell lines and may play a significant role in tumor suppression through promotion of cell apoptosis. The gene encoding PIG11 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11. Alternative Name :
p53 induced gene 11 protein; p53 induced protein; PIG 11; PIG11; Tumor protein p53 inducible protein 11; Swiss-Prot :
O14683 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PIG11 (P93). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1865 PIG11 (P93) pAb.
PIG11 (P93) Peptide Applications :
Blocking Background :
PIG11 (p53-induced gene 11 protein), also known as TP53I11, is a 177 amino acid tumor suppressor belonging to the p53-induced protein gene (PIG) family. The PIG gene family encodes redox-controlling proteins that are involved in p53 tumor suppressor activity. It is suggested that PIG11 is involved in arsenic trioxide As(2)O(3)-induced apoptosis in certain cell lines and may play a significant role in tumor suppression through promotion of cell apoptosis. The gene encoding PIG11 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11. Alternative Name :
p53 induced gene 11 protein; p53 induced protein; PIG 11; PIG11; Tumor protein p53 inducible protein 11; Swiss-Prot :
O14683 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PIG11 (P93). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1865 PIG11 (P93) pAb.
Blocking peptide available as BS1865PP