Product Name :
GAK (Q129) Peptide Applications :
Blocking Background :
Cyclin D1 accumulates during G1 and associates with Cdk2, Cdk4 and Cdk5. Cyclin E and Cdk2 interact during the G1 to S transition. Cyclin G contains a typical N terminal cyclin box and a carboxy terminal domain sequence homologous to the tyrosine phosphorylation site of the epidermal growth factor receptor). Cyclin G expression is induced within 3 hours after growth stimulation and remains elevated with no apparent cell cycle dependency. A serine/threonine kinase, designated GAK for cyclin G associated kinase, has been identified. GAK has been shown to bind directly to cyclin G and to co-immunoprecipitate with Cdk5, which also associates with cyclin G. Alternative Name :
Auxilin 2; Cyclin G associated kinase; Cyclin-G-associated kinase; DNAJ26; DNAJC26; EC 2.7.11.1; FLJ16629; FLJ40395; GAK; GAK protein; MGC99654; Swiss-Prot :
O14976 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide GAK (Q129). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1871 GAK (Q129) pAb.
GAK (Q129) Peptide Applications :
Blocking Background :
Cyclin D1 accumulates during G1 and associates with Cdk2, Cdk4 and Cdk5. Cyclin E and Cdk2 interact during the G1 to S transition. Cyclin G contains a typical N terminal cyclin box and a carboxy terminal domain sequence homologous to the tyrosine phosphorylation site of the epidermal growth factor receptor). Cyclin G expression is induced within 3 hours after growth stimulation and remains elevated with no apparent cell cycle dependency. A serine/threonine kinase, designated GAK for cyclin G associated kinase, has been identified. GAK has been shown to bind directly to cyclin G and to co-immunoprecipitate with Cdk5, which also associates with cyclin G. Alternative Name :
Auxilin 2; Cyclin G associated kinase; Cyclin-G-associated kinase; DNAJ26; DNAJC26; EC 2.7.11.1; FLJ16629; FLJ40395; GAK; GAK protein; MGC99654; Swiss-Prot :
O14976 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide GAK (Q129). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1871 GAK (Q129) pAb.
Blocking peptide available as BS1871PP