ZIS (I144) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
ZIS (I144) Peptide Applications :
Blocking Background :
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF265 (Zinc finger protein 265), also known as ZRANB2 (Zinc finger Ran-binding domain-containing protein 2), ZIS, ZIS1 or ZIS2, is a 330 amino acid protein that belongs to the ZRANB2 family. Localized to the nucleus, ZNF265 functions as a splicing factor that is responsible for alternatively splicing Tra-2β (transformer-2 beta) transcripts and is thought to interfere with constitutive 5’-splice selection. ZNF265 contains two RanBP2-type zinc fingers through which it conveys its RNA-binding activity. Two isoforms, designated ZIS-1 and ZIS-2, are expressed due to alternative splicing events. Upon DNA damage, ZIS-2 may be phosphorylated by ATM or ATR. Alternative Name :
ZRANB 2; Zinc finger protein 265; Zinc finger RAN binding domain containing 2; Zinc finger Ran binding domain containing protein 2; Zinc finger splicing; ZIS; ZIS1; ZIS2; ZNF265; Swiss-Prot :
O95218 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ZIS (I144). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1900 ZIS (I144) pAb.
ZIS (I144) Peptide Applications :
Blocking Background :
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF265 (Zinc finger protein 265), also known as ZRANB2 (Zinc finger Ran-binding domain-containing protein 2), ZIS, ZIS1 or ZIS2, is a 330 amino acid protein that belongs to the ZRANB2 family. Localized to the nucleus, ZNF265 functions as a splicing factor that is responsible for alternatively splicing Tra-2β (transformer-2 beta) transcripts and is thought to interfere with constitutive 5’-splice selection. ZNF265 contains two RanBP2-type zinc fingers through which it conveys its RNA-binding activity. Two isoforms, designated ZIS-1 and ZIS-2, are expressed due to alternative splicing events. Upon DNA damage, ZIS-2 may be phosphorylated by ATM or ATR. Alternative Name :
ZRANB 2; Zinc finger protein 265; Zinc finger RAN binding domain containing 2; Zinc finger Ran binding domain containing protein 2; Zinc finger splicing; ZIS; ZIS1; ZIS2; ZNF265; Swiss-Prot :
O95218 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ZIS (I144). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1900 ZIS (I144) pAb.
Blocking peptide available as BS1900PP