TCF-4/12 (S616) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
TCF-4/12 (S616) Peptide Applications :
Blocking Background :
T cell factors (TCFs) comprise a family of DNA-binding transcriptional activators that are essential for lymphoid cell development. These transcription factors are activated by the Wnt-1 and Wingless pathways and are characterized by the presence of a conserved protein motif, the high mobility group (HMG) 1 box, which mediates DNA binding. TCF-4 mainly localizes in the cytoplasm and is transported into the nucleus directly bound to β-catenin in a cooperative manner. This TCF-4/β-catenin complex induces expression of Wnt target genes, including multiple cancer-associated genes. Alternative Name :
ITF 2; ITF2; PTHS; SEF 2; SEF2 1; SEF2 1A; SEF2 1B; SEF2; TCF4; HTF4; HsT17266; HEB; E box binding protein; Transcription factor 12; Transcription factor HTF-4; Swiss-Prot :
P15884/Q99081 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TCF-4/12 (S616). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1934 TCF-4/12 (S616) pAb.
TCF-4/12 (S616) Peptide Applications :
Blocking Background :
T cell factors (TCFs) comprise a family of DNA-binding transcriptional activators that are essential for lymphoid cell development. These transcription factors are activated by the Wnt-1 and Wingless pathways and are characterized by the presence of a conserved protein motif, the high mobility group (HMG) 1 box, which mediates DNA binding. TCF-4 mainly localizes in the cytoplasm and is transported into the nucleus directly bound to β-catenin in a cooperative manner. This TCF-4/β-catenin complex induces expression of Wnt target genes, including multiple cancer-associated genes. Alternative Name :
ITF 2; ITF2; PTHS; SEF 2; SEF2 1; SEF2 1A; SEF2 1B; SEF2; TCF4; HTF4; HsT17266; HEB; E box binding protein; Transcription factor 12; Transcription factor HTF-4; Swiss-Prot :
P15884/Q99081 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TCF-4/12 (S616). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1934 TCF-4/12 (S616) pAb.
Blocking peptide available as BS1934PP