Hox-B9 (R237) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Hox-B9 (R237) Peptide Applications :
Blocking Background :
The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Themammalian Hox gene complex consists of 39 genes that are located on four linkage groups, which are dispersed over four chromosomes. Hox genes that occupy the same relative position along the 5' to 3' coordinate (trans-paralogous genes) are more similar in sequence and expression pattern than adjacent Hox genes on the same chromosome. In mice, the HoxB cluster contains HoxB1 to HoxB9 and HoxB13, which are transcribed in the same direction. HoxB9 associates with the transcriptional cofactors BTG1 and BTG2, which enhance HoxB9 ranscription. Alterations in HoxB9 expression, as with other Hox family member, has been implicated in leukemia. Alternative Name :
Hox-2E; Hox-2.5; HOXB9; HOX2E Swiss-Prot :
P17482 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Hox-B9 (R237). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1940 Hox-B9 (R237) pAb.
Hox-B9 (R237) Peptide Applications :
Blocking Background :
The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Themammalian Hox gene complex consists of 39 genes that are located on four linkage groups, which are dispersed over four chromosomes. Hox genes that occupy the same relative position along the 5' to 3' coordinate (trans-paralogous genes) are more similar in sequence and expression pattern than adjacent Hox genes on the same chromosome. In mice, the HoxB cluster contains HoxB1 to HoxB9 and HoxB13, which are transcribed in the same direction. HoxB9 associates with the transcriptional cofactors BTG1 and BTG2, which enhance HoxB9 ranscription. Alterations in HoxB9 expression, as with other Hox family member, has been implicated in leukemia. Alternative Name :
Hox-2E; Hox-2.5; HOXB9; HOX2E Swiss-Prot :
P17482 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Hox-B9 (R237). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1940 Hox-B9 (R237) pAb.
Blocking peptide available as BS1940PP