Product Name :
PITSLRE (K20) Peptide Applications :
Blocking Background :
The PITSLRE β1 protein, a distantly related member of the Cdk family of protein kinases, induces apoptosis after low levels of ectopic expression. Apoptosis, or programmed cell death, is similarly induced by ectopic expression of an amino terminal deletion mutant retaining the catalytic and carboxy terminal domains of PITSLRE β1, but not by other mutants lacking Histone H1 kinase activity or by other Cdk family members. The terminology for the ten isoforms of the PITSLRE subfamily of proteins is based on the conserved PSTAIRE box region of Cdc2 p34. Depending on which of the PITSLRE genes produce the protein, the cDNA and protein are designated α, β or γ (i.e., PITSLRE A gene, α; PITSLRE B gene, β and PITSLRE C gene, γ). Some of the isoforms such as PITSLRE α1 (T cells) and PITSLRE β1 (B cells and brain), are expressed in specific cell types, while others are expressed ubiquitously. Alternative Name :
CDC2L2; CDC2L3; CDK11; CDK11 p110; CDK11 p46; CDK11 p58; CDK11A; CDK8 like cyclin dependent kinase; Cell division cycle 2 like 2 (PITSLRE proteins); Cell division cycle 2 like protein kinase 2; Cell division cycle 2-like protein kinase 2; Cell division protein kinase 11A; Cyclin dependent kinase (CDC2 like) 11; Cyclin-dependent kinase 11A; Death preventing kinase; Galactosyltransferase associated protein kinase p58/GTA; Galactosyltransferase-associated protein kinase p58/GTA; p5 Swiss-Prot :
P21127 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PITSLRE (K20). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1951 PITSLRE (K20) pAb.
PITSLRE (K20) Peptide Applications :
Blocking Background :
The PITSLRE β1 protein, a distantly related member of the Cdk family of protein kinases, induces apoptosis after low levels of ectopic expression. Apoptosis, or programmed cell death, is similarly induced by ectopic expression of an amino terminal deletion mutant retaining the catalytic and carboxy terminal domains of PITSLRE β1, but not by other mutants lacking Histone H1 kinase activity or by other Cdk family members. The terminology for the ten isoforms of the PITSLRE subfamily of proteins is based on the conserved PSTAIRE box region of Cdc2 p34. Depending on which of the PITSLRE genes produce the protein, the cDNA and protein are designated α, β or γ (i.e., PITSLRE A gene, α; PITSLRE B gene, β and PITSLRE C gene, γ). Some of the isoforms such as PITSLRE α1 (T cells) and PITSLRE β1 (B cells and brain), are expressed in specific cell types, while others are expressed ubiquitously. Alternative Name :
CDC2L2; CDC2L3; CDK11; CDK11 p110; CDK11 p46; CDK11 p58; CDK11A; CDK8 like cyclin dependent kinase; Cell division cycle 2 like 2 (PITSLRE proteins); Cell division cycle 2 like protein kinase 2; Cell division cycle 2-like protein kinase 2; Cell division protein kinase 11A; Cyclin dependent kinase (CDC2 like) 11; Cyclin-dependent kinase 11A; Death preventing kinase; Galactosyltransferase associated protein kinase p58/GTA; Galactosyltransferase-associated protein kinase p58/GTA; p5 Swiss-Prot :
P21127 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PITSLRE (K20). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1951 PITSLRE (K20) pAb.
Blocking peptide available as BS1951PP