Myf-6 (R150) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Myf-6 (R150) Peptide Applications :
Blocking Background :
Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development includes Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Most muscle cells express either Myo D or Myf-5 in the committed state, but when induced to differentiate, all turn on expression of myogenin. Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes. Alternative Name :
bHLHc4; Class C basic helix-loop-helix protein 4; HERCULIN; MRF4; Muscle-specific regulatory factor 4; Myf-6; Myf6; MYF6; Myogenic factor 6; Swiss-Prot :
P23409 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Myf-6 (R150). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1956 Myf-6 (R150) pAb.
Myf-6 (R150) Peptide Applications :
Blocking Background :
Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development includes Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Most muscle cells express either Myo D or Myf-5 in the committed state, but when induced to differentiate, all turn on expression of myogenin. Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes. Alternative Name :
bHLHc4; Class C basic helix-loop-helix protein 4; HERCULIN; MRF4; Muscle-specific regulatory factor 4; Myf-6; Myf6; MYF6; Myogenic factor 6; Swiss-Prot :
P23409 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Myf-6 (R150). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1956 Myf-6 (R150) pAb.
Blocking peptide available as BS1956PP