FEN1 (A119) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
FEN1 (A119) Peptide Applications :
Blocking Background :
DNA replication, recombination and repair, all of which are necessary for genome stability, require the presence of exonucleases. In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. FEN-1 (for flap endonuclease) is an endonuclease that specifically cleaves the 5' flap structure of DNA in the process of DNA repair. FEN-1 is highly homologous to yeast Rad2. The C-terminal region of FEN-1 may bind to PCNA, thus allowing FEN-1 to function as an exonuclease in DNA replication. Alternative Name :
FEN-1; EC 3.1.-.-; Flap structure-specific endonuclease 1; Maturation factor 1; MF1; hFEN-1; DNase IV; FEN1; Flap endonuclease. FEN-1. Flap exonuclease. FEN1. Five prime Exonuclease Swiss-Prot :
P39748 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide FEN1 (A119). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1989 FEN1 (A119) pAb.
FEN1 (A119) Peptide Applications :
Blocking Background :
DNA replication, recombination and repair, all of which are necessary for genome stability, require the presence of exonucleases. In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. FEN-1 (for flap endonuclease) is an endonuclease that specifically cleaves the 5' flap structure of DNA in the process of DNA repair. FEN-1 is highly homologous to yeast Rad2. The C-terminal region of FEN-1 may bind to PCNA, thus allowing FEN-1 to function as an exonuclease in DNA replication. Alternative Name :
FEN-1; EC 3.1.-.-; Flap structure-specific endonuclease 1; Maturation factor 1; MF1; hFEN-1; DNase IV; FEN1; Flap endonuclease. FEN-1. Flap exonuclease. FEN1. Five prime Exonuclease Swiss-Prot :
P39748 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide FEN1 (A119). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1989 FEN1 (A119) pAb.
Blocking peptide available as BS1989PP