Product Name :
MEK-6 (Q3) Peptide Applications :
Blocking Background :
A family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway. Alternative Name :
Dual specificity mitogen-activated protein kinase kinase 4; MAP kinase kinase 4; JNK-activating kinase 1; c-Jun N-terminal kinase kinase 1; JNKK; SAPK/ERK kinase 1; SEK1; MAP2K4; JNKK1; MKK4; PRKMK4; SERK1; Swiss-Prot :
P52564 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide MEK-6 (Q3). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2013 MEK-6 (Q3) pAb.
MEK-6 (Q3) Peptide Applications :
Blocking Background :
A family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway. Alternative Name :
Dual specificity mitogen-activated protein kinase kinase 4; MAP kinase kinase 4; JNK-activating kinase 1; c-Jun N-terminal kinase kinase 1; JNKK; SAPK/ERK kinase 1; SEK1; MAP2K4; JNKK1; MKK4; PRKMK4; SERK1; Swiss-Prot :
P52564 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide MEK-6 (Q3). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2013 MEK-6 (Q3) pAb.
Blocking peptide available as BS2013PP