SRY (L80) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
SRY (L80) Peptide Applications :
Blocking Background :
SRY (sex-determining region Y protein) is a transcriptional activator required for male sex determination in mammals. This protein, also referred to as testis-determining factor (TDF), is an HMG box protein that initiates the formation of testis from undifferentiated gonad. The DNA-binding activity of SRY is required for normal testis formation. This DNA-binding activity is thought to be regulated by PKA, which phosphorylates SRY in vivo. Mutations in SRY have been associated with 46,XY gonadal dysgenesis, in which the gonads fail to develop in XY phenotypic females. Alternative Name :
SRY (Sex determining region Y)-box 13. isoform CRA_b; SOX13; RP11-74C13.1. ICA12. MGC117216. SRY-box 13. Sox-13 Swiss-Prot :
Q05066 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide SRY (L80). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2037 SRY (L80) pAb.
SRY (L80) Peptide Applications :
Blocking Background :
SRY (sex-determining region Y protein) is a transcriptional activator required for male sex determination in mammals. This protein, also referred to as testis-determining factor (TDF), is an HMG box protein that initiates the formation of testis from undifferentiated gonad. The DNA-binding activity of SRY is required for normal testis formation. This DNA-binding activity is thought to be regulated by PKA, which phosphorylates SRY in vivo. Mutations in SRY have been associated with 46,XY gonadal dysgenesis, in which the gonads fail to develop in XY phenotypic females. Alternative Name :
SRY (Sex determining region Y)-box 13. isoform CRA_b; SOX13; RP11-74C13.1. ICA12. MGC117216. SRY-box 13. Sox-13 Swiss-Prot :
Q05066 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide SRY (L80). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2037 SRY (L80) pAb.
Blocking peptide available as BS2037PP