TEF (K224) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
TEF (K224) Peptide Applications :
Blocking Background :
TEF (thyrotrophic embryonic factor), also known as KIAA1655, is a 303 amino acid nuclear transcription factor that belongs to the bZIP (basic region/leucine zipper) family and PAR (proline and acidic amino acid-rich) subfamily. TEF binds DNA as either a homodimer or heterodimer, and is known to transactivate the TSHβ promoter. While broadly expressed in adults, TEF is only found in developing embryonic anterior pituitary gland. TEF accumulates according to a robust circadian rhythm and has also been found to inhibit cell growth by downregulating β chain expression of cytokine receptors. The functional domains of TEF are highly homologous with other members of the PAR-bZIP subfamily, including albumin D box-binding protein (DABP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP). The gene encoding TEF maps to human chromosome 22q13.2. Alternative Name :
Tef; TEF; tefa; tefb; tefbeta; thyrotroph embryonic factor; VBP; Swiss-Prot :
Q10587 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TEF (K224). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2041 TEF (K224) pAb.
TEF (K224) Peptide Applications :
Blocking Background :
TEF (thyrotrophic embryonic factor), also known as KIAA1655, is a 303 amino acid nuclear transcription factor that belongs to the bZIP (basic region/leucine zipper) family and PAR (proline and acidic amino acid-rich) subfamily. TEF binds DNA as either a homodimer or heterodimer, and is known to transactivate the TSHβ promoter. While broadly expressed in adults, TEF is only found in developing embryonic anterior pituitary gland. TEF accumulates according to a robust circadian rhythm and has also been found to inhibit cell growth by downregulating β chain expression of cytokine receptors. The functional domains of TEF are highly homologous with other members of the PAR-bZIP subfamily, including albumin D box-binding protein (DABP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP). The gene encoding TEF maps to human chromosome 22q13.2. Alternative Name :
Tef; TEF; tefa; tefb; tefbeta; thyrotroph embryonic factor; VBP; Swiss-Prot :
Q10587 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TEF (K224). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2041 TEF (K224) pAb.
Blocking peptide available as BS2041PP