Treacle (Q55) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Treacle (Q55) Peptide Applications :
Blocking Background :
Treacle is a serine/alanine-rich 1,411 amino acid nuclear phosphoprotein that interacts with upstream binding factor (UBF) and affects transcription of the ribosomal DNA gene. Treacle is also involved in early embryonic development, particularly in the craniofacial complex, and may play a role in nucleolarcytoplasmic transport. The Treacle protein contains three domains with unique N- and C-termini and a large central repeat domain. Mutations in TCOF1, the gene that encodes for Treacle, cause Treacher Collins-Franceschetti syndrome (TCS), a disorder characterized by defects in craniofacial development. Symptoms of TCS include conductive hearing loss, hypoplasia of the mandible and maxilla, downward sloping palpebral fissures and cleft palate. Alternative Name :
MFD1; TCOF 1; TCOF; TCOF1; Treacher Collins syndrome protein; Treacle; Treacle protein; Swiss-Prot :
Q13428 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Treacle (Q55). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2047 Treacle (Q55) pAb.
Treacle (Q55) Peptide Applications :
Blocking Background :
Treacle is a serine/alanine-rich 1,411 amino acid nuclear phosphoprotein that interacts with upstream binding factor (UBF) and affects transcription of the ribosomal DNA gene. Treacle is also involved in early embryonic development, particularly in the craniofacial complex, and may play a role in nucleolarcytoplasmic transport. The Treacle protein contains three domains with unique N- and C-termini and a large central repeat domain. Mutations in TCOF1, the gene that encodes for Treacle, cause Treacher Collins-Franceschetti syndrome (TCS), a disorder characterized by defects in craniofacial development. Symptoms of TCS include conductive hearing loss, hypoplasia of the mandible and maxilla, downward sloping palpebral fissures and cleft palate. Alternative Name :
MFD1; TCOF 1; TCOF; TCOF1; Treacher Collins syndrome protein; Treacle; Treacle protein; Swiss-Prot :
Q13428 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Treacle (Q55). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2047 Treacle (Q55) pAb.
Blocking peptide available as BS2047PP