Smad4 (L43) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Smad4 (L43) Peptide Applications :
Blocking Background :
Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MadH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members. Alternative Name :
SMAD 4; hSMAD4; Deletion target in pancreatic carcinoma 4; SMAD4; DPC4; MADH4 Swiss-Prot :
Q13485 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Smad4 (L43). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2050 Smad4 (L43) pAb.
Smad4 (L43) Peptide Applications :
Blocking Background :
Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MadH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members. Alternative Name :
SMAD 4; hSMAD4; Deletion target in pancreatic carcinoma 4; SMAD4; DPC4; MADH4 Swiss-Prot :
Q13485 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Smad4 (L43). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2050 Smad4 (L43) pAb.
Blocking peptide available as BS2050PP