FoxJ1 (T295) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
FoxJ1 (T295) Peptide Applications :
Blocking Background :
Forkhead-box J1 (FOXJ1) is a 421-amino acid transcription factor that suppresses T cell activity and thus spontaneous autoimmunity, through the repression of NF˚B activity. FOXJ1 also inhibits the humoral immune response in B cells; FOXJ1 deficiency in B cells results in spontaneous and accentuated germinal center formation, implicated in the development of pathogenic autoantibodies and accentuated responses to immunizations. Abnormal expression of FOXJ1 may be associated with autoimmune diseases and/or other inflammatory diseases. FOXJ1 is also required for cilia formation and left-right axis determination because it increases calpastatin expression, a protein necessary for the ability of basal bodies to anchor to the apical cytoskeleton. FOXJ1 expression may function as an early marker of epithelial cell differentiation, recovery, and function. Alternative Name :
FKHL13; forkhead box J1; Fox J1; FoxJ1; HFH 4; HFH-4; HFH4; Swiss-Prot :
Q92949 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide FoxJ1 (T295). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2116 FoxJ1 (T295) pAb.
FoxJ1 (T295) Peptide Applications :
Blocking Background :
Forkhead-box J1 (FOXJ1) is a 421-amino acid transcription factor that suppresses T cell activity and thus spontaneous autoimmunity, through the repression of NF˚B activity. FOXJ1 also inhibits the humoral immune response in B cells; FOXJ1 deficiency in B cells results in spontaneous and accentuated germinal center formation, implicated in the development of pathogenic autoantibodies and accentuated responses to immunizations. Abnormal expression of FOXJ1 may be associated with autoimmune diseases and/or other inflammatory diseases. FOXJ1 is also required for cilia formation and left-right axis determination because it increases calpastatin expression, a protein necessary for the ability of basal bodies to anchor to the apical cytoskeleton. FOXJ1 expression may function as an early marker of epithelial cell differentiation, recovery, and function. Alternative Name :
FKHL13; forkhead box J1; Fox J1; FoxJ1; HFH 4; HFH-4; HFH4; Swiss-Prot :
Q92949 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide FoxJ1 (T295). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2116 FoxJ1 (T295) pAb.
Blocking peptide available as BS2116PP