Product Name :
Mnk1 (I136) Peptide Applications :
Blocking Background :
The MAPKAP kinases (for MAP kinase activated protein kinases) are a group of MAP kinase substrates which are themselves kinases. In response to activation, the MAP kinases phosphorylate downstream components on a consensus Pro-X-Ser/Thr-Pro motif. Several kinases that contain this motif have been identifed and serve as substrates for the ERK and p38 MAP kinases. These include the serine/threonine kinases Rsk-1 (also designated MAPKAP kinase-1), Rsk-2 and Rsk-3, which are phosphorylated by ERK1 and ERK2. Similarly p38 phosphorylates and activates the serine/threonine kinases MAPKAP kinase-2 and MAPKAP kinase-3 (also designated 3pK). The serine/threonine kinases Mnk1 and Mnk2 are substrates for both ERK and p38 MAP kinases. Alternative Name :
MAP kinase-interacting serine/threonine-protein kinase 1; MAP kinase signal-integrating kinase 1; Mnk1; MKNK1; MNK1; Swiss-Prot :
Q9BUB5 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Mnk1 (I136). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2133 Mnk1 (I136) pAb.

• 

Blocking peptide available as BS2133PP