Product Name :
CD318 / CDCP1 (K721) Peptide Applications :
Blocking Background :
CDCP1 (CUB-domain-containing protein 1) contains three extracellular CUB domains, a transmembrane domain and two putative cytoplasmic tyrosine phosphorylation sites. Phosphorylation of the gp140 and p80 proteins is mediated by Src family kinases at various tyrosine residues, including Tyr 734. PTP family members mediate the desphosphorylation of CDCP1. The conversion of gp140 to p80 prolongs the phosphorylation state, which may affect signaling in epithelial wounds. CDCP1 acts as a marker for hematopoetic cells and also exhibits high expression in metastatic colon and breast tumors. Alternative Name :
CDCP1; CD318; SIMA135; TRASK Swiss-Prot :
Q9H5V8 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CD318 / CDCP1 (K721). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2141 CD318 / CDCP1 (K721) pAb.
CD318 / CDCP1 (K721) Peptide Applications :
Blocking Background :
CDCP1 (CUB-domain-containing protein 1) contains three extracellular CUB domains, a transmembrane domain and two putative cytoplasmic tyrosine phosphorylation sites. Phosphorylation of the gp140 and p80 proteins is mediated by Src family kinases at various tyrosine residues, including Tyr 734. PTP family members mediate the desphosphorylation of CDCP1. The conversion of gp140 to p80 prolongs the phosphorylation state, which may affect signaling in epithelial wounds. CDCP1 acts as a marker for hematopoetic cells and also exhibits high expression in metastatic colon and breast tumors. Alternative Name :
CDCP1; CD318; SIMA135; TRASK Swiss-Prot :
Q9H5V8 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CD318 / CDCP1 (K721). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2141 CD318 / CDCP1 (K721) pAb.
Blocking peptide available as BS2141PP