SPT16 (S967) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
SPT16 (S967) Peptide Applications :
Blocking Background :
FACT is a chromatin-specific elongation factor required for transcription of chromatin templates, and it specifically interacts with nucleosomes and histone H2A/H2B dimers, to promote nucleosome disassembly upon transcription. FACT represents a complex between SPT16, a homologue of the Saccharomyces cerevisiae Spt16/Cdc68 protein, and the high-mobility group (HMG)-1-like protein structure-specific recognition protein-1 (SSRP-1). Similar to other (HMG) domain containing proteins, which are characterized by their ability to bend target DNAs, SSRP1 and the murine ortholog T160, physically interact with serum response factors (SRF) and function as a positive co regulatory proteins involved in modulating SRF-dependent gene expression. Alternative Name :
CDC68; FACT; hSPT16; Supt16h; Swiss-Prot :
Q9Y5B9 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide SPT16 (S967). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2174 SPT16 (S967) pAb.
SPT16 (S967) Peptide Applications :
Blocking Background :
FACT is a chromatin-specific elongation factor required for transcription of chromatin templates, and it specifically interacts with nucleosomes and histone H2A/H2B dimers, to promote nucleosome disassembly upon transcription. FACT represents a complex between SPT16, a homologue of the Saccharomyces cerevisiae Spt16/Cdc68 protein, and the high-mobility group (HMG)-1-like protein structure-specific recognition protein-1 (SSRP-1). Similar to other (HMG) domain containing proteins, which are characterized by their ability to bend target DNAs, SSRP1 and the murine ortholog T160, physically interact with serum response factors (SRF) and function as a positive co regulatory proteins involved in modulating SRF-dependent gene expression. Alternative Name :
CDC68; FACT; hSPT16; Supt16h; Swiss-Prot :
Q9Y5B9 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide SPT16 (S967). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2174 SPT16 (S967) pAb.
Blocking peptide available as BS2174PP