Cofilin1/2 (T88) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Cofilin1/2 (T88) Peptide Applications :
Blocking Background :
Cofilin is ubiquitously expressed in eukaryotic cells where it binds to Actin,thereby regulating the rapid cycling of Actin assembly and disassembly essential for cellular viability. Cofilin is a low molecular weight protein that binds to filamentous F-Actin by bridging two longitudinally associated Actin subunits changing the F-Actin filament twist. This process is allowed by the dephosphorylation of Cofilin Ser 3 by factors such as opsonized zymosan.Lim kinase 1, a serine kinase, phosphorylates Cofilin and renders it unable to bind and depolymerise F-Actin. Alternative Name :
Cofilin-1; Cofilin1; Cofilin 1; 18 kDa phosphoprotein; p18; Cofilin, non-muscle isoform; CFL1; CFL; Cofilin-2; Cofilin2; Cofilin 2; Cofilin, muscle isoform; CFL2 Swiss-Prot :
Q9Y281/P23528 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Cofilin1/2 (T88). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2183 Cofilin1/2 (T88) pAb.
Cofilin1/2 (T88) Peptide Applications :
Blocking Background :
Cofilin is ubiquitously expressed in eukaryotic cells where it binds to Actin,thereby regulating the rapid cycling of Actin assembly and disassembly essential for cellular viability. Cofilin is a low molecular weight protein that binds to filamentous F-Actin by bridging two longitudinally associated Actin subunits changing the F-Actin filament twist. This process is allowed by the dephosphorylation of Cofilin Ser 3 by factors such as opsonized zymosan.Lim kinase 1, a serine kinase, phosphorylates Cofilin and renders it unable to bind and depolymerise F-Actin. Alternative Name :
Cofilin-1; Cofilin1; Cofilin 1; 18 kDa phosphoprotein; p18; Cofilin, non-muscle isoform; CFL1; CFL; Cofilin-2; Cofilin2; Cofilin 2; Cofilin, muscle isoform; CFL2 Swiss-Prot :
Q9Y281/P23528 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Cofilin1/2 (T88). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2183 Cofilin1/2 (T88) pAb.
Blocking peptide available as BS2183PP