Product Name :
Cadherin-18 (Q129) Peptide Applications :
Blocking Background :
This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Alternative Name :
Cadherin 18; Cadherin-14; CDH18; CDH14; Cadherin18; Cadherin 14; Cadherin14 Swiss-Prot :
Q13634 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Cadherin-18 (Q129). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2222 Cadherin-18 (Q129) pAb.
Cadherin-18 (Q129) Peptide Applications :
Blocking Background :
This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Alternative Name :
Cadherin 18; Cadherin-14; CDH18; CDH14; Cadherin18; Cadherin 14; Cadherin14 Swiss-Prot :
Q13634 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Cadherin-18 (Q129). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2222 Cadherin-18 (Q129) pAb.
Blocking peptide available as BS2222PP