Product Name :
N-Cadherin (W745) Peptide Applications :
Blocking Background :
Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2-terminal repeats. The most distal of these cadherins is thought to be responsible for binding specificity, transmembrane domains and carboxyterminal intracellular domains. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as β-catenin, to regulate cadherin function. Members of this family of adhesion proteins include rat cadherin K (and its human homolog, cadherin-6), R-cadherin, B-cadherin, E/P-cadherin and cadherin-5. Alternative Name :
Cadherin2; Cadherin 2; Cadherin-2; CDw325; Neural cadherin; N-cadherin; CD325; CDH2; CDHN; NCAD Swiss-Prot :
P19022 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide N-Cadherin (W745). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2224 N-Cadherin (W745) pAb.
N-Cadherin (W745) Peptide Applications :
Blocking Background :
Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2-terminal repeats. The most distal of these cadherins is thought to be responsible for binding specificity, transmembrane domains and carboxyterminal intracellular domains. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as β-catenin, to regulate cadherin function. Members of this family of adhesion proteins include rat cadherin K (and its human homolog, cadherin-6), R-cadherin, B-cadherin, E/P-cadherin and cadherin-5. Alternative Name :
Cadherin2; Cadherin 2; Cadherin-2; CDw325; Neural cadherin; N-cadherin; CD325; CDH2; CDHN; NCAD Swiss-Prot :
P19022 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide N-Cadherin (W745). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2224 N-Cadherin (W745) pAb.
Blocking peptide available as BS2224PP