Product Name :
Maspin (T118) Peptide Applications :
Blocking Background :
Maspin is structurally a serine protease inhibitor (serpin) that was initially isolated from normal human mammary epithelial cells. Serpins are a family of proteins that inhibit chymotrypsin-like serine proteinases. Serpins control activated proteinases and several are involved in the regulation of cell death. Maspin is found in the extracellular matrix and at the plasma membrane. Maspin has been shown to act at the cell surface to block cell motility and inhibit invasion of breast and prostate cancer cells. Maspin is present in normal mammary epithelial cells but is absent in many tumor cell lines, yet no major structural alterations of the Maspin gene have been identified in tumor cells. Similarly, Maspin is expressed in normal prostate cells and downregulated or absent in prostate tumor cells.. Alternative Name :
mammary serine proteinase inhibitor; Maspin; Ovalbumin; Peptidase inhibitor 5; PI-5; PI5; Protease inhibitor 5; Serine (or cysteine) peptidase inhibitor; clade B; member 5; Serpin B5; serpin peptidase inhibitor; Serpin peptidase inhibitor; clade B (ovalbumin); member 5; SERPINB5; SPB5; Spi5; Spi7; Swiss-Prot :
P36952 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Maspin (T118). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2233 Maspin (T118) pAb.
Maspin (T118) Peptide Applications :
Blocking Background :
Maspin is structurally a serine protease inhibitor (serpin) that was initially isolated from normal human mammary epithelial cells. Serpins are a family of proteins that inhibit chymotrypsin-like serine proteinases. Serpins control activated proteinases and several are involved in the regulation of cell death. Maspin is found in the extracellular matrix and at the plasma membrane. Maspin has been shown to act at the cell surface to block cell motility and inhibit invasion of breast and prostate cancer cells. Maspin is present in normal mammary epithelial cells but is absent in many tumor cell lines, yet no major structural alterations of the Maspin gene have been identified in tumor cells. Similarly, Maspin is expressed in normal prostate cells and downregulated or absent in prostate tumor cells.. Alternative Name :
mammary serine proteinase inhibitor; Maspin; Ovalbumin; Peptidase inhibitor 5; PI-5; PI5; Protease inhibitor 5; Serine (or cysteine) peptidase inhibitor; clade B; member 5; Serpin B5; serpin peptidase inhibitor; Serpin peptidase inhibitor; clade B (ovalbumin); member 5; SERPINB5; SPB5; Spi5; Spi7; Swiss-Prot :
P36952 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Maspin (T118). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2233 Maspin (T118) pAb.
Blocking peptide available as BS2233PP