Product Name :
Rad23A (R119) Peptide Applications :
Blocking Background :
The RAD23 genes (RAD23A and RAD23B), which encode the human Rad23 proteins, are crucial for excision-repair of UV-damaged DNA. RAD23 genes resemble the other DNA repair genes, RAD2, RAD6, RAD7, RAD18 and RAD54, all of which also exhibit increased transcription in response to DNA damage and during meiosis. Rad23 is a nuclear protein containing an ubiquitin-like domain required for biological functions. The protein, which is highly conserved, is involved in nucleotide excision repair (NER) that associates with the proteasome via its N-terminus. The C-terminal ubiquitin-associated domain of Rad23 is evolutionarily conserved from yeast to humans. Rad23 may also act as a regulator for the activity of the 26S Proteasome. Alternative Name :
hHR 23A; hHR23A; HR23A; MGC111083; RAD 23a; RAD23 homolog A; RAD23 yeast homolog A; RAD23A; RD23A; UV excision repair protein RAD23; UV excision repair protein RAD23 homolog A Swiss-Prot :
P54725 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Rad23A (R119). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2236 Rad23A (R119) pAb.
Rad23A (R119) Peptide Applications :
Blocking Background :
The RAD23 genes (RAD23A and RAD23B), which encode the human Rad23 proteins, are crucial for excision-repair of UV-damaged DNA. RAD23 genes resemble the other DNA repair genes, RAD2, RAD6, RAD7, RAD18 and RAD54, all of which also exhibit increased transcription in response to DNA damage and during meiosis. Rad23 is a nuclear protein containing an ubiquitin-like domain required for biological functions. The protein, which is highly conserved, is involved in nucleotide excision repair (NER) that associates with the proteasome via its N-terminus. The C-terminal ubiquitin-associated domain of Rad23 is evolutionarily conserved from yeast to humans. Rad23 may also act as a regulator for the activity of the 26S Proteasome. Alternative Name :
hHR 23A; hHR23A; HR23A; MGC111083; RAD 23a; RAD23 homolog A; RAD23 yeast homolog A; RAD23A; RD23A; UV excision repair protein RAD23; UV excision repair protein RAD23 homolog A Swiss-Prot :
P54725 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Rad23A (R119). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2236 Rad23A (R119) pAb.
Blocking peptide available as BS2236PP