Product Name :
TAF II p135/p105 (E977) Peptide Applications :
Blocking Background :
TAF II p105, also called TAF4B, is a celltype specific transcriptional co-activator that is a component of the TFIID complex. Expressed primarily in B cells and ovarian granulosa cells, TAF II p105 can interact with OCBA/POU2AF1 to activate B cell-specific octamerdependent transcription. Additionally, TAF II p105 plays an important role in co-activating the transcription factor NFκB and is essential for activation of anti-apoptotic genes such as TNFAIP3. TAF II p135, also known as TAF4, TAF2C, TAF2C1, TAF4A or TAFII130, is a 1,085 amino acid subunit of TFIID that accelerates transcriptional activation triggered by thyroid hormone (TR) or retinoic acid (RA). Localized to the nucleus, TAF II p135 contains one TAFH domain and is thought to bind to proteins that contain glutamine-rich domains, such as the transcription factor CREB. Alternative Name :
TAF(II)135; TAF2C; TAF2C1; TAF4A; TAFII 130; TAFII 135; TAFII130; TAFII135; TBP associated factor 4; TBP Associated transcription Factor family member; Transcription initiation factor TFIID 135 kDa subunit; Transcription initiation factor TFIID subunit 4; Swiss-Prot :
O00268/Q92750 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TAF II p135/p105 (E977). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2239 TAF II p135/p105 (E977) pAb.
TAF II p135/p105 (E977) Peptide Applications :
Blocking Background :
TAF II p105, also called TAF4B, is a celltype specific transcriptional co-activator that is a component of the TFIID complex. Expressed primarily in B cells and ovarian granulosa cells, TAF II p105 can interact with OCBA/POU2AF1 to activate B cell-specific octamerdependent transcription. Additionally, TAF II p105 plays an important role in co-activating the transcription factor NFκB and is essential for activation of anti-apoptotic genes such as TNFAIP3. TAF II p135, also known as TAF4, TAF2C, TAF2C1, TAF4A or TAFII130, is a 1,085 amino acid subunit of TFIID that accelerates transcriptional activation triggered by thyroid hormone (TR) or retinoic acid (RA). Localized to the nucleus, TAF II p135 contains one TAFH domain and is thought to bind to proteins that contain glutamine-rich domains, such as the transcription factor CREB. Alternative Name :
TAF(II)135; TAF2C; TAF2C1; TAF4A; TAFII 130; TAFII 135; TAFII130; TAFII135; TBP associated factor 4; TBP Associated transcription Factor family member; Transcription initiation factor TFIID 135 kDa subunit; Transcription initiation factor TFIID subunit 4; Swiss-Prot :
O00268/Q92750 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TAF II p135/p105 (E977). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2239 TAF II p135/p105 (E977) pAb.
Blocking peptide available as BS2239PP