TFIIA-α (E311) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
TFIIA-α (E311) Peptide Applications :
Blocking Background :
Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFIIH. Recognition of the TATA binding element by TBP, one of the first steps in transcription initiation, may be regulated by TFIIA. TFIIA consists of three subunits designated TFIIA-α, TFIIA-β and TFIIA-γ, and it interacts with both TBP and a TAF (TBP-associated factor). It has been demonstrated that the basic region of TBP is essential for TFIIA-dependent function of TBP. Alternative Name :
General transcription factor II A. 1-like factor; ALF; MGC26254 Swiss-Prot :
P52655 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TFIIA-α (E311). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2282 TFIIA-α (E311) pAb.
TFIIA-α (E311) Peptide Applications :
Blocking Background :
Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFIIH. Recognition of the TATA binding element by TBP, one of the first steps in transcription initiation, may be regulated by TFIIA. TFIIA consists of three subunits designated TFIIA-α, TFIIA-β and TFIIA-γ, and it interacts with both TBP and a TAF (TBP-associated factor). It has been demonstrated that the basic region of TBP is essential for TFIIA-dependent function of TBP. Alternative Name :
General transcription factor II A. 1-like factor; ALF; MGC26254 Swiss-Prot :
P52655 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TFIIA-α (E311). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2282 TFIIA-α (E311) pAb.
Blocking peptide available as BS2282PP