PBF (R151) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
PBF (R151) Peptide Applications :
Blocking Background :
PBF, also known as PTTG1IP (pituitary tumor-transforming 1 interacting protein), is a 180 amino acid single-pass type I membrane protein that localizes both the cytoplasm and the nucleus and contains a coiled-coil domain. Expressed ubiquitously, PBF interacts with PTTG and is thought to facilitate the nuclear translocation of PTTG, thereby allowing the PTTG-dependent transcriptional activation of fibroblast growth factor (FGF). The gene encoding PBF maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1.5% of the human genome. Chromosome 21-associated disorders include Alzheimer’s disease, amyotrophic lateral sclerosis and, most notably, Down syndrome (also known as trisomy 21). Alternative Name :
PTTG binding factor; PTTG-binding factor; PTTG; Pttg1ip; PBF; PTTG1IP Swiss-Prot :
P53801 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PBF (R151). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2285 PBF (R151) pAb.
PBF (R151) Peptide Applications :
Blocking Background :
PBF, also known as PTTG1IP (pituitary tumor-transforming 1 interacting protein), is a 180 amino acid single-pass type I membrane protein that localizes both the cytoplasm and the nucleus and contains a coiled-coil domain. Expressed ubiquitously, PBF interacts with PTTG and is thought to facilitate the nuclear translocation of PTTG, thereby allowing the PTTG-dependent transcriptional activation of fibroblast growth factor (FGF). The gene encoding PBF maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1.5% of the human genome. Chromosome 21-associated disorders include Alzheimer’s disease, amyotrophic lateral sclerosis and, most notably, Down syndrome (also known as trisomy 21). Alternative Name :
PTTG binding factor; PTTG-binding factor; PTTG; Pttg1ip; PBF; PTTG1IP Swiss-Prot :
P53801 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PBF (R151). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2285 PBF (R151) pAb.
Blocking peptide available as BS2285PP