DMPK (R30) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
DMPK (R30) Peptide Applications :
Blocking Background :
Myotonic dystrophy protein kinase (DMPK) is a ulti-domain protein kinase found in muscle that is activated in response to G protein second messengers and proteolysis. DMPK is implicated in myotonic muscular dystrophy (DM), an autosomal dominant-inherited disorder that predominately affects skeletal and cardiac muscle and causes defects in cardiac conduction. DM arises through expansion of CTG repeats in the 3’-UTR of the DMPK gene. Mutant DMPK transcripts with an extended region of CUG repeats are retained in the nucleus. These transcripts also influence the expression of the DM locus-associated homeodomain protein (DMAHP)/SIX5, to mediate in part the DM phenotype. Other substrates for DMPK include myogenin, Ltype calcium channels, and Phospholemman (PLM). Alternative Name :
DMPK; DM; DM-KINASE; DM1; DM1PK; DMK; EC 2.7.11.1; MDPK; MT-PK Swiss-Prot :
Q09013 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide DMPK (R30). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2298 DMPK (R30) pAb.
DMPK (R30) Peptide Applications :
Blocking Background :
Myotonic dystrophy protein kinase (DMPK) is a ulti-domain protein kinase found in muscle that is activated in response to G protein second messengers and proteolysis. DMPK is implicated in myotonic muscular dystrophy (DM), an autosomal dominant-inherited disorder that predominately affects skeletal and cardiac muscle and causes defects in cardiac conduction. DM arises through expansion of CTG repeats in the 3’-UTR of the DMPK gene. Mutant DMPK transcripts with an extended region of CUG repeats are retained in the nucleus. These transcripts also influence the expression of the DM locus-associated homeodomain protein (DMAHP)/SIX5, to mediate in part the DM phenotype. Other substrates for DMPK include myogenin, Ltype calcium channels, and Phospholemman (PLM). Alternative Name :
DMPK; DM; DM-KINASE; DM1; DM1PK; DMK; EC 2.7.11.1; MDPK; MT-PK Swiss-Prot :
Q09013 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide DMPK (R30). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2298 DMPK (R30) pAb.
Blocking peptide available as BS2298PP