Product Name :
CDK10 (E63) Peptide Applications :
Blocking Background :
Cdk10, also called PISSLRE, is a Cdc2-related kinase whose gene has been shown to encode two isoforms, each having a different function within the cell cycle. Although the two isoforms share nearly identical amino acid seqeunces, they differ at the C- and N- terminals. One Cdk isoform interacts with the transcription factor Ets-2, thereby modulating its transactivation activity, while the other is thought to have a role at the G2/M transition. Cdk10 mRNA has been shown to have the highest expression in lung, liver and kidney tissue, with gene upregulation implicated in cases of non-Hodgkin’s follicular lymphoma. Alternative Name :
Cyclin-dependent kinase 10; Cell division protein kinase 10; Serine/threonine-protein kinase PISSLRE; CDK10 Swiss-Prot :
Q15131 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CDK10 (E63) . (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2312 CDK10 (E63) pAb .
CDK10 (E63) Peptide Applications :
Blocking Background :
Cdk10, also called PISSLRE, is a Cdc2-related kinase whose gene has been shown to encode two isoforms, each having a different function within the cell cycle. Although the two isoforms share nearly identical amino acid seqeunces, they differ at the C- and N- terminals. One Cdk isoform interacts with the transcription factor Ets-2, thereby modulating its transactivation activity, while the other is thought to have a role at the G2/M transition. Cdk10 mRNA has been shown to have the highest expression in lung, liver and kidney tissue, with gene upregulation implicated in cases of non-Hodgkin’s follicular lymphoma. Alternative Name :
Cyclin-dependent kinase 10; Cell division protein kinase 10; Serine/threonine-protein kinase PISSLRE; CDK10 Swiss-Prot :
Q15131 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CDK10 (E63) . (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2312 CDK10 (E63) pAb .
Blocking peptide available as BS2312PP