Product Name :
TAF I p48 (R318) Peptide Applications :
Blocking Background :
For gene transcription governed by RNA polymerase I, the human transcription factor SL1 (mouse TIF-IB) directs the assembly of initiation complexes at the prompter. Like TFIID, which directs transcription by RNA polymerase II, SL1/TIF-IB contains the TATA-binding protein (TBP) and a set of TBP-associated factors (TAFs). The three TAF I subunits, hTAF I p110, hTAF I p63 and hTAF p48 (or mouse TAF I p95, TAF I p68 and TAF I p48) are all integral components of SL1/TIF-IB. The mutually exclusive binding of either TAF I or TAF II subunits to TBP is believed to direct the formation of promoter and RNA polymerase-specific complexes. Alternative Name :
SET; 2PP2A; I-2PP2A; I2PP2A; IGAAD; PHAPII; TAF-I; TAF-IBETA Swiss-Prot :
Q15573 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TAF I p48 (R318). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2313 TAF I p48 (R318) pAb.
TAF I p48 (R318) Peptide Applications :
Blocking Background :
For gene transcription governed by RNA polymerase I, the human transcription factor SL1 (mouse TIF-IB) directs the assembly of initiation complexes at the prompter. Like TFIID, which directs transcription by RNA polymerase II, SL1/TIF-IB contains the TATA-binding protein (TBP) and a set of TBP-associated factors (TAFs). The three TAF I subunits, hTAF I p110, hTAF I p63 and hTAF p48 (or mouse TAF I p95, TAF I p68 and TAF I p48) are all integral components of SL1/TIF-IB. The mutually exclusive binding of either TAF I or TAF II subunits to TBP is believed to direct the formation of promoter and RNA polymerase-specific complexes. Alternative Name :
SET; 2PP2A; I-2PP2A; I2PP2A; IGAAD; PHAPII; TAF-I; TAF-IBETA Swiss-Prot :
Q15573 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TAF I p48 (R318). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2313 TAF I p48 (R318) pAb.
Blocking peptide available as BS2313PP