Translin (E121) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Translin (E121) Peptide Applications :
Blocking Background :
Translin, also designated testis brain RNA-binding protein (TB-RBP), is a single-stranded DNA- and RNA-binding protein that binds to the 3' UTR regions (Y and H elements) of stored mRNAs, which suppresses their in vitro translation. The human translin gene maps to chromosome 2q21.1 and encodes a 26 kDa protein that has been highly conserved throughout evolution. Translin forms a ring-shaped structure, which is responsible for DNA binding, and also contains a leucine zipper motif, which is thought to enable translin to form dimers. Translin exports specific mRNAs out of the nucleus, supported by its localization in both the nuclei and cytoplasm of neurons, and regulates their translation. Alternative Name :
Translin; EC=3.1.-.-; Component 3 of promoter of RISC; C3PO; TSN Swiss-Prot :
Q15631 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Translin (E121). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2314 Translin (E121) pAb.
Translin (E121) Peptide Applications :
Blocking Background :
Translin, also designated testis brain RNA-binding protein (TB-RBP), is a single-stranded DNA- and RNA-binding protein that binds to the 3' UTR regions (Y and H elements) of stored mRNAs, which suppresses their in vitro translation. The human translin gene maps to chromosome 2q21.1 and encodes a 26 kDa protein that has been highly conserved throughout evolution. Translin forms a ring-shaped structure, which is responsible for DNA binding, and also contains a leucine zipper motif, which is thought to enable translin to form dimers. Translin exports specific mRNAs out of the nucleus, supported by its localization in both the nuclei and cytoplasm of neurons, and regulates their translation. Alternative Name :
Translin; EC=3.1.-.-; Component 3 of promoter of RISC; C3PO; TSN Swiss-Prot :
Q15631 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Translin (E121). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS2314 Translin (E121) pAb.
Blocking peptide available as BS2314PP